The Basilica of the Sacred Heart in the university of Notre Dame, Indiana serves as the university's church as well as the mother church of the Congregation of Holy Cross. The neo-gothic church features 44 large stained glass windows and murals completed over a 17 year period by Vatican painter Luigi Gregori.

The current Basilica of the Sacred Heart building was begun in 1870 and consecrated by Bishop Joseph Dwenger on August 15, 1888. In 1968, the church was renovated with the intention of bringing it to line with the liturgical reform of the Second Vatican Council. The Basilica again received a renovation 20 years later executed by Conrad Schmitt Studios. The conservation and restoration of the historic stained glass windows, created in LeMans, France, was one of the studio’s largest single projects, with 116 windows and over 1200 panels of glass. On January 17, 1992, Pope John Paul II raised the Church of the Sacred Heart to the status of Basilica. This status helps make it a popular destination for pilgrims and tourists to the site, who number around 50000 per year.

For many of the Saturdays, each year, four sets of brides and grooms are married in the Basilica of the Sacred Heart starting at 9:00 AM with ceremonies following at 11:00 AM, 1:00 PM and 3:00 PM. Three wedding ceremonies are also held on many Fridays of the year.